Tramadol: Balancing Pain Relief and Safety in Clinical Practice
Disease State Management/Drug Therapy CE for Pharmacist & Pharmacy Techs
Monograph
Course Summary
Tramadol is a synthetic, schedule IV opioid that is used for the treatment of acute and long-term pain, and as an analgesic agent in perioperative clinical settings. Tramadol is widely prescribed in the US and worldwide. Its historical popularity was partly due to its perceived favorable side effects profile and safety, and the perception that it was less likely to be misused than other short-acting opioids; however, tramadol may be just as misused as other opioids. Tramadol remains a popular drug to prescribe, and it does provide positive patient outcomes when it is used properly; however, it is not indicated for all patient populations, and for some patients, dosing should be adjusted. Because of tramadol's pharmacodynamics, it can cause an accidental overdose. In these cases, tramadol can cause serious morbidities and death.
Describe the basic pharmacological profile, use, and clinical outcomes of tramadol treatment
Identify the dosing for tramadol for the treatment of acute and long-term pain
Compare the benefits and risks of tramadol compared to other drugs used to treat acute and long-term pain
Identify the contraindications and potential side effects of tramadol
Course Syllabus
- Introduction
- Clinical Overview of Tramadol
- History and Controlled Status
- Pharmacologic Profile
- Indications and Uses
- Formulations and Dosing
- Tramadol Safety Considerations
- Adverse Effects of Tramadol
- Boxed Warnings and Contraindications
- Additional Warnings and Clinical Considerations
- Tramadol Use in Special Populations
- Pediatrics
- Older Adults
- Hepatic or Renal Impairment
- Pregnancy and Breastfeeding
- Tramadol Misuse and Overdose
- Tramadol Use Disorder
- Tramadol Overdose
- Patient Case
- Summary
- Read the course objectives and faculty planner disclosure
- Read the course material
- Complete the post-test with a minimum score of 70% and complete the course evaluation form.
- Results are automatically submitted to CPE Monitor
Faculty Planner Disclosure
The following individuals were involved in planning, developing, and/or authoring this activity: L. Austin Fredrickson, MD, FACP; Sandra Rogers, MD; Kelsey Giara, PharmD, RPh; and Pamela Sardo, PharmD, BS. None of the individuals involved in developing this activity has a conflict of interest or financial relationships related to the subject matter. There are no financial relationships or commercial or financial support relevant to this activity to report or disclose by RxCe.com or any of the individuals involved in the development of this activity.
Unlabeled Use Disclosures
The information provided in this course is general in nature, and it is designed solely to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant's professional practice, including but not limited to patient assessment, diagnosis, treatment, and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice. Healthcare professionals must consult their employer, healthcare facility, hospital, or other organization for guidelines, protocols, and procedures to follow. The information provided in this course does not replace those guidelines, protocols, and procedures, but is for academic purposes only, and this course's limited purpose is for the completion of continuing education credits. Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses is constantly changing. Any person taking this course understands that such a person must make an independent review of medication information before any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only, and such uses are not endorsed hereby. Nothing contained in this course represents the opinions, views, judgments, or conclusions of RxCe.com LLC. RxCe.com LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course or course material.
Computer Hardware/Software Requirements
Please ensure the device you plan to use meets these requirements and specifications:
- Operating System: Windows 7,8,10, or 11 /Mac OS X 10.9 or later/iOS/Android
- Supported Browsers: Microsoft Edge, Firefox, Google Chrome, Safari, Opera
- A connection to the internet
- For Live Webinars or Conferences: GoToWebinar application for iOS, Android, Mac, or PC. You cannot 'call into' a live conference.
- Target Audience: Pharmacist, Pharmacy Tech
- Secondary Audiences: This educational activity is also for other healthcare professionals, such as nurses, physicians, or others who may be part of a healthcare team and may be interested in this educational topic. A healthcare team approach to patient care may be discussed in this activity, as applicable. No state board or professional organization has evaluated this activity to determine whether it meets the continuing education requirements of nurses, physicians, or other professions not listed under the “Target Audience” described above. Always verify with individual employers or supervisors whether they will accept this educational activity upon completion.
- Contact Hours: 3.00 (0.30 CEUs)
- Activity Release Date: 3/2/2026
- Activity Expiration Date: 3/2/2029
- Activity Type: Knowledge and Application
- UAN: JA4008424-0000-26-021-H01-P
- Topic: Disease State Management/Drug Therapy
- UAN Number: (Techs): JA4008424-0000-26-021-H01-T
- CeBroker Number: 20-1362087
Faculty:
RxCe.com, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
RxCe.com, LLC, offers pharmacy technician continuing education courses for PTCB recertification. Pharmacy technician courses are indicated both in the Target Audience description and the ACPE UAN which will end with a "T".